The Cosmetic vs Skin Aging vs Beauty from the Outside


Skin Aging

The skin is probably the organ that is most susceptible to damage produced
by free radicals because of its contact with oxygen and with other environmental
stimuli. It reveals the first signs of physical aging at around age 30.
But skin aging does not affect only the elderly; it affects everyone because
people sunbathe too much. It is not only the passing of time that makes us
age, but the accumulation of deleterious chemical events that deteriorate our
bodies into the condition that we call aging. The aging process, which
reduces the number of healthy cells, is soon visible on the skin. On facial
skin, the cumulative and inexorable process of aging is there for all to see.
The damage produced by free radicals impairs the cells’ ability to transport
nutrients, eliminate waste products, and reproduce adequately, and results in
the accumulation of by-products, such as pigment lipofuscin (age spots),
interfering with their normal functions. Moreover, too much sun exposure
increases the production of free radicals, which, in tum, increases inflammation,
and the degradation rates of collagen and elastin, thereby resulting in
accelerated aging.
Thus, anti-aging products and global facial skincare remain the cosmetic
category’s growth driver (Fig. 5.4), by an increase of7.6% in the U.S., 7%

Global facial skincare sales (in billion dollars) from 2002 to 2005.
Source: Euromonitor.

in Western Europe, 9% in the Asia Pacific region, 21.6% in Eastern Europe,
19.7% in Latin America, and 8.2% in Africa and the Middle East. Socalled
cosmeceuticals and doctor brands continue to be a major feature of
the skincare segment [17].

The Cosmetic Challenge

In an attempt to defeat the undesirable effects of aging and photoaging,
cosmetologists have developed many new cosmetic formulas, keeping
abreast of what happens in the areas of biology and biochemistry and
using increasingly sophisticated and active raw materials [18]. As a result,
moisturizing and protective micro- and nano-emulsions containing vitamins
A, E, B, C, collagen and its derivatives have been proposed (Fig. 5.5).
Interesting studies have been conducted on peptides from gelatin enriched
with glycine, which turned out to be very active, increasing moisturizing
activity and reducing the inexorable process of skin aging (Fig. 5.6) [19,20].
A double-blind clinical study recently showed that gelatin-glycine may
increase the moisturizing activity of lutein [21], which is currently pointed
to as an active compound in skin aging [22].
Scientific evidence has been presented that shows the benefits of hydrolyzed
collagen (gelatin), used both in cosmetics and in diet supplements,
in preserving joint health. This is because both the topical application and
the ingestion of hydrolyzed collagen may increase the pool of amino acids
and peptides that are useful for collagen synthesis. Moreover, gelatin may
also have a specific stimulating effect on the production of collagen by the

Moisturizing activity of gelatin-glycerine (gel-gly) plus
vitamins and oligoelements (vit-ol).

Moisturizing activity of gelatin-glycerine (gel-gly).

joint cells themsel ves [23]. Collagen is a structural protein of the body that
ensures cohesion, elasticity, and regeneration of the skin, cartilage, and
bone, which declines in terms of quality and quantity during the aging
Ceramide polymer is a new ingredient developed in Japan (Nof Co.) to
help improve the elasticity and smoothness of skin. This polymer has a
high affinity with the skin, and thanks to its similarity to natural ceramides,
it can reinvigorate the skin and restore its softness and elasticity [24].
Goldschmidt (Germany) has proposed a hydrolyzed sodium hyaluronate
obtained through the fermentation of Bacillus sublitis to improve the skin’s
elasticity and to reduce wrinkles. Vitamin B6, an innovative liposoluble
that serves as an enhancer of filagrin production, was presented this year
by Jon Dekker (USA) at In Cosmetics. The hydrolyzed oat polypeptide
obtained by enzymatic hydrolysis from Kelisema (Italy) seems to protect
the stratum corneum against irritations and may be a solution for skin
Because consumers expect beauty and personal care products to provide
them with a unique sensory experience before, during, and after application,
Dow Coming (USA) has created specialized silicium polymers providing
lubricity, emolliency, and moisturization both for skin and hair. Silicium
plays an important role in connective tissues; the finding that it is a component
of human glycosaminoglycans and their protein complexes suggests
that this mineral plays a structural role. Indeed, silicium contributes to the
structural framework of connective tissues by forming links or bridges
within and between individual polysaccharide chains and perhaps by linking
polysaccharide chains to proteins (Fig. 5.7) [25,26]. In this way, this
mineral compound may help build the architecture of the fibrous elements
of connective tissues and may contribute to their structural integrity by
providing strength and resilience.
Chitin nanofibrils [27-30] are cosmetic components or pharmaceutical
carriers that help to restore the integrity of the skin barrier and to increase
the ability to link and retain water contained in the comeocytes (Fig. 5.8).
They are used in cosmetic and/or pharmaceutical solutions or emulsions
to stimulate the formation of a molecular film that slows down water
evaporation and helps to keep the skin perfectly hydrated.
Their mechanism of action can be considered active because they repair
the intercomeocitary cement that joins both ceramides and phospholipids

Model of the arrangement of fibronectin, collagen, and
proteoglycans in the extracellular matrix showing the role of silicon.

Photomicrograph of a chitin nanofibril at a magnification of

to form the lipidic lamellae. Moreover, these nanofibrils are easily recognized
by the cutaneous enzymes and hydrolyzed. In this way, the
N-acetyl glucosamine content can regulate collagen synthesis in fibroblasts,
also facilitating the granulation and repair of the altered skin
tissue [31,32]. Thus, nanotechnology is now present also in consumer
products (Fig. 5.9).

Presence of nanotechnology-enabled consumer products in
the health and fitness arena. Source: Woodrow Wilson Center Nanotech
Project Inventory.

Needless to say, thousands of active principles are used in cosmetic
products. However, “natural and organic skin care is undergoing somewhat
of a revolution, involving issues such as the environment. The integrity
of ingredients and holistic well-being strike a chord with more and
more consumers”

Author : kaabinet



48 thoughts on “The Cosmetic vs Skin Aging vs Beauty from the Outside”

  1. It’s perfect time to make some plans for the longer term and it’s time
    to be happy. I’ve read this submit and if I may I desire
    to suggest you some fascinating issues or advice. Perhaps you can write subsequent articles regarding this article.
    I desire to read even more things approximately it!

  2. When someone writes an post he/she retains the idea of a user in his/her brain that
    how a user can know it. So that’s why this article is perfect.

  3. I believe this is among the so much important info for me.
    And i’m satisfied studying your article. However should statement on few general issues,
    The site taste is great, the articles is in point of fact nice : D.
    Just right job, cheers

  4. Hello everybody, here every person is sharing these kinds of familiarity, therefore it’s good to read
    this webpage, and I used to pay a visit this blog everyday.

  5. Having read this I believed it was very enlightening.
    I appreciate you taking the time and energy to put this content together.
    I once again find myself spending a lot of time both reading
    and commenting. But so what, it was still worthwhile!

  6. Admiring the time and effort you put into your blog and in depth information you present.
    It’s great to come across a blog every once in a while that isn’t the same old rehashed information.
    Fantastic read! I’ve bookmarked your site and I’m adding your RSS feeds to
    my Google account.

  7. you are in point of fact a just right webmaster. The website
    loading pace is amazing. It kind of feels that you’re
    doing any distinctive trick. Furthermore, The contents are masterpiece.
    you’ve performed a fantastic activity on this matter!

  8. I was curious if you ever considered changing the structure of your
    blog? Its very well written; I love what youve got to say.

    But maybe you could a little more in the way of content so
    people could connect with it better. Youve got an awful lot of text
    for only having one or 2 images. Maybe you could space it out better?

  9. Good post. I learn something totally new and challenging on websites I stumbleupon everyday.
    It will always be useful to read content from other writers and practice
    a little something from their websites.

  10. Hey I know this is off topic but I was wondering if you
    knew of any widgets I could add to my blog that automatically tweet my newest twitter updates.
    I’ve been looking for a plug-in like this for
    quite some time and was hoping maybe you would have some experience with something like this.
    Please let me know if you run into anything.
    I truly enjoy reading your blog and I look forward to your new

  11. I’m not positive where you are getting your info, but great topic.

    I needs to spend some time studying more or working out more.

    Thank you for great information I used to be on the
    lookout for this information for my mission.

  12. Very nice post. I just stumbled upon your blog and
    wanted to say that I’ve truly enjoyed browsing your blog
    posts. In any case I’ll be subscribing to your rss
    feed and I hope you write again very soon! plenty of fish natalielise

  13. Hi there! I just wanted to ask if you ever have any trouble with hackers?
    My last blog (wordpress) was hacked and I ended up losing many months of hard work due to no data backup.
    Do you have any methods to stop hackers? pof natalielise

  14. Hi, Neat post. There is an issue along with your website in internet
    explorer, might test this? IE nonetheless is the marketplace leader and a huge component to other people will leave
    out your magnificent writing because of this problem.

  15. Greetings from Idaho! I’m bored at work so I decided to check out your site
    on my iphone during lunch break. I really like the info you provide here
    and can’t wait to take a look when I get home. I’m surprised
    at how quick your blog loaded on my mobile .. I’m not even using WIFI, just 3G ..
    Anyways, very good site!

  16. Do you mind if I quote a couple of your articles as long
    as I provide credit and sources back to your weblog?
    My blog site is in the very same area of interest as yours and my visitors would truly benefit
    from some of the information you present here. Please let
    me know if this ok with you. Thank you!

  17. Whats up this is kinda of off topic but I was wanting to know if blogs use WYSIWYG editors or if
    you have to manually code with HTML. I’m starting a blog soon but
    have no coding expertise so I wanted to get guidance from someone with experience.
    Any help would be enormously appreciated!

  18. Excellent beat ! I would like to apprentice while you amend your
    web site, how could i subscribe for a blog
    website? The account aided me a acceptable deal. I had been a little
    bit acquainted of this your broadcast offered bright clear concept

  19. What’s Happening i’m new to this, I stumbled upon this I have discovered It absolutely helpful and it has helped me out loads.
    I’m hoping to contribute & assist different users like its helped me.

    Great job.

  20. Thank you for any other informative website. Where else may just
    I get that type of info written in such a perfect method?
    I’ve a venture that I am simply now working on, and I’ve been at the glance out for such information.

  21. My spouse and I stumbled over here different web address and thought I might check things out.
    I like what I see so i am just following you.
    Look forward to going over your web page repeatedly.

  22. I’m impressed, I must say. Rarely do I encounter a blog that’s
    both educative and entertaining, and let me tell you, you have hit the nail on the head.
    The issue is an issue that too few people are speaking intelligently about.

    Now i’m very happy that I stumbled across this in my hunt for something relating to

  23. Do you mind if I quote a couple of your posts as long
    as I provide credit and sources back to your site? My website
    is in the very same area of interest as yours and my visitors would
    truly benefit from some of the information you provide here.
    Please let me know if this okay with you. Thanks!

  24. Fantastic beat ! I would like to apprentice even as you amend your web site, how could i subscribe for a weblog website?
    The account helped me a appropriate deal.
    I were tiny bit acquainted of this your broadcast offered vivid clear concept

Leave A Reply